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Artelis - Trainee Scientist
Realization of my Master Thesis: "Développement d'un bioprocédé visant la culture, à l'échelle industrielle, de cardiomyoblastes pour une application en thérapie cellulaire" focus on the development of a bioprocess aiming the cardiomyoblast expansion at industrial scale for cell therapy application.

The main objective of the thesis was to:
- Evaluate single-use sensor technology for its application in the large-scale single-use bioreactor.
- Develop cell culture protocol (cell seeding, growth and harvest) in a small-scale prototype bioreactor.
- Evaluate the shear stress profile applied on the cell layer.

Artelis - Junior Scientist
As Junior Scientist, I was focus on the development of a single-use bioreactor dedicated for Cell Therapy Applications.
As Engineer in Biochemistry, my mission was to work with the Automation team and the Cell Culture team in order to translate Cell Culture needs/requirements to technical solution taking into account the constraints highlighted by the Automation team.
In a second time, I also participated to project aiming the production of virus in single-use bioreactor for Vaccine Applications

Artelis / ATMI LF - Applicaion Support
As Application Support, my responsibilities were:
- Listen customer and understand his needs/targets.
- Install and qualify equipment.
- Ensure training of customers.
- Establish an experimental plan in order to transfer the customer's process to our single-use technologies and improve production yield.

This required closed, professional and transparent contact with our customers.
During this mission, I had the opportunity to travel around the world and meet valuable experts in the Cell Therapy and Vaccines fields.

Masthercell - Technical Service Supervisor
I joined Masthercell in 2014 as Technical Service Supervisor to build the Technical Service Department.

My responsibilities were:
- Managing the equipment lifecycle according to cGMP regulation including HVAC systems and Production Room Qualification.
- Managing warehousing and procurement.
- Putting in place SOP to manage all Technical Service responsibilities.

During this mission, I was also involved in additional project such as:
- Scale-out feasibility study in Quantum bioreactors.
- Implementation of ERP system to manage Accounting, Procurement and Inventory.

Masthercell - Development Engineer
2 years later having started my collaboration with Masthercell and thanks to the success of the Quantum project, I was promoted to Project Management Department as Development Engineer in order to promote Development service of the company as CDMO.
My mission was the development of bioprocess that will address the long-term industrialization of the cell therapy in terms of GMP constraints and cost.

Phacilitate's Interview

Masthercell - IT Manager
Following the company growth and thanks to my previous experience, I was promoted to create the IT department of Masthercell.

I put in place SOP compliant with cGMP and Sox regulations to ensure:
- Computerized System Lifecycle (V-approach)
- Access Control Management
- Business continuity and disaster recovery plan

My responsibilities were (not exhaustive list):
- Manage annual budget (OPEX and CAPEX)
- Manage a team of 6 people with different expertise/profile (BI - Developers - Admin System)
- Introduce the concept of Industry 4.0 to the company.

Masthercell / Catalent - Senior IT Manager
After 3 years of successful projects (see My Realization section), I was promoted as Senior IT Manager.

Asdaex - Sr. Project Manager
Managing Automation projects for Pharmaceutical Industry from the quote to the solution delivery.
My current responsibilities are:
- Planning generation according to client deadline and tasks to achieved (GAMP 5 - V-Approach).
- Implement validation strategy according to customer's SOP.
- Risk assessment and management
- Schedule adherence, resources and budget control.
- People relation.
- Technical support for specification, development and computerized system validation